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For plasma membrane preparation, cells were homogenized by the Ultrathurax in buffer (20 mM Na-HEPES, 0.1 mM EDTA (pH = 7.4)) and stored at 80 C until usage

Clinical trials have used doses of 25-30 nmol/kg by IV infusion (Schneider-Helmert et al., 1981Subcutaneous administration and oral intestinal absorption have also been studied

Quick Answer: Emerging observational evidence suggests GLP-1 receptor agonists may be associated with reduced depression symptoms, though they are not licensed for mental health treatment and require further research

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